College Course · Pre-Med · MCAT·Semester 1 & 2 · McMurry / Klein syllabus

Organic ChemistryOrgo 1 & 2 — Complete Course Coverage

The most feared pre-med course — made visual and interactive. Free simulations, a full interactive ebook for all 22 chapters, and timed practice sets. Whether you're in Orgo 1, Orgo 2, or prepping for the MCAT, everything is free.

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Orgo 1
~14–16 weeks · Semester 1
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Orgo 2
~14–16 weeks · Semester 2
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Audience
Pre-Med · Chem · Bio majors
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MCAT
Covers all Orgo on exam
📊 Data-Driven Strategy·1,125 real exam problems analyzed

The single biggest finding

Two chapters — Alkene Reactions (24.5%) and Stereochemistry (23.9%) — make up nearly half of every Orgo 1 exam. Add Acid-Base (17.8%) and Functional Groups (13.7%) and four chapters account for roughly 80% of what's tested.

Orgo 1 — Chapters 1–11

Orgo 1 Exams

CU Boulder, Dartmouth, MNSU & compiled practice archives · n = 1,059 questions

Alkenes — Reactions & Synthesis
24.5%
Stereochemistry
23.9%
Acids & Bases
17.8%
Functional Groups & Reactivity
13.7%
Alkyl Halides & Nucleophilic Substitution
9.3%
Bonding & Molecular Structure
6.1%
Other
4.8%
Orgo 2 — Chapters 12–22

Orgo 2 Exams

Early sample · aromatic + carbonyl-heavy archives · n = 66 questions

Aldehydes & Ketones
60.6%
Spectroscopy & Structure Determination
16.7%
Electrophilic Aromatic Substitution
10.6%
Alkenes — Reactions & Synthesis
4.5%
Functional Groups & Reactivity
3%
Acids & Bases
3%
Alkyl Halides & Nucleophilic Substitution
1.5%

Note: our Orgo 2 sample (66 problems) is much smaller than Orgo 1's (1,059) — most of the free university archives we found so far skew toward Orgo 1. This will get more representative as we source more Orgo 2 exams.

Ready to prepare?

Complete Chapter Roadmap

22 chapters across Orgo 1 & 2 — the ebook and test bank will follow this structure exactly.

Orgo 1 — Semester 1 · Chapters 1–11
Ch1

Bonding & Molecular Structure

Hybridization (sp, sp², sp³), Lewis structures, formal charge, resonance

Ch2

Acids & Bases in Organic Chemistry

pKₐ scale, conjugate pairs, predicting reaction direction, resonance/induction effects

Ch3

Functional Groups & Overview

Alkanes, alkenes, alkynes, alcohols, ethers, carbonyls, amines — identification & naming

Ch4

Alkanes & Cycloalkanes

IUPAC naming, conformational analysis, Newman projections, ring strain, cis/trans isomers

Ch5

Stereochemistry

Chirality, stereocenters, R/S configuration, enantiomers, diastereomers, meso compounds, optical activity

Ch6

Alkyl Halides & Nucleophilic Substitution

SN1 and SN2 mechanisms, stereochemical outcomes, leaving groups, nucleophile strength, solvent effects

Ch7

Elimination Reactions

E1 and E2 mechanisms, Zaitsev's rule, anti periplanar requirement, competition with substitution

Ch8

Alkenes — Reactions & Synthesis

Markovnikov addition, carbocation stability, hydration, halogenation, hydroboration-oxidation, ozonolysis

Ch9

Alkynes

Terminal vs internal, acidity of terminal H, reduction to alkene, hydration (Markovnikov & anti-Markovnikov)

Ch10

Alcohols & Ethers

Synthesis, oxidation states, Williamson ether synthesis, epoxides, acid/base ring-opening

Ch11

Conjugated Systems & Diels-Alder

1,2 vs 1,4 addition, resonance in dienes, Diels-Alder cycloaddition, endo/exo selectivity

Orgo 2 — Semester 2 · Chapters 12–22
Ch12

Aromatic Compounds

Benzene structure, aromaticity, Hückel's rule, antiaromaticity, resonance stabilization

Ch13

Electrophilic Aromatic Substitution

Halogenation, nitration, sulfonation, Friedel-Crafts alkylation/acylation, ortho/para/meta directors

Ch14

Nucleophilic Aromatic Substitution

Addition-elimination mechanism, benzyne pathway, activating groups required

Ch15

Spectroscopy & Structure Determination

IR (functional group ID), ¹H NMR (chemical shift, splitting, integration), ¹³C NMR, mass spectrometry (m/z, fragmentation)

Ch16

Aldehydes & Ketones

Nucleophilic addition, acetal/hemiacetal formation, imines, enamines, Wittig reaction, cyanohydrins

Ch17

Carboxylic Acids

Acidity (pKₐ), synthesis, Hell-Volhard-Zelinsky, decarboxylation, Fischer esterification

Ch18

Carboxylic Acid Derivatives

Esters, amides, anhydrides, acyl chlorides — acyl substitution mechanism, hydrolysis, saponification, Claisen condensation

Ch19

Enolates & Alpha Chemistry

Aldol condensation, Claisen condensation, Michael addition, Robinson annulation, Dieckmann

Ch20

Amines

Basicity, synthesis (reductive amination, Gabriel synthesis), reactions, diazonium salts, coupling reactions

Ch21

Carbohydrates

Monosaccharide classification, Fischer projections, Haworth structures, anomers, glycosidic bonds, disaccharides

Ch22

Amino Acids & Peptides

Structure, pKₐ and isoelectric point, peptide bond formation, N-/C-terminus, protein structure intro

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Orgo is the #1 Pre-Med Weed-Out
Over 30% of pre-med students fail or drop Orgo 1. Mechanisms, stereochemistry, and reaction patterns require a different kind of thinking than general chemistry.
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MCAT Covers All of Orgo 1 & 2
The MCAT Chemical & Physical Foundations section tests the entire Orgo 1 & 2 curriculum. Strong Orgo fundamentals directly translate to MCAT points.
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JEE Orgo → Orgo 1 & 2 Mapping
If you've studied JEE Advanced organic chemistry, you've already covered 90% of Orgo 1 & 2. The depth and difficulty of Orgo 2 is below JEE Advanced level.

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