The isoelectric point of a protein is the pH at which it is electrically neutral. Which mutation of — Biochemistry Chemistry Question
Question
The isoelectric point of a protein is the pH at which it is electrically neutral. Which mutation of an amino acid NH2CHRCOOH in the protein would have the greatest effect on its isoelectric point, assuming that the mutation does not significantly affect the protein’s overall structure?
A.✓ Correct
Serine (R = CH2OH) Lysine (R = CH2CH2CH2CH2NH2)
B.
Glutamine (R = CH2CH2CONH2) Methionine (R = CH2CH2SCH3)
C.
Isoleucine (R = CH[CH3]CH2CH3) Valine (R = CH[CH3]2)
D.
Alanine (R = CH3) Glycine (R = H)
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